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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e3566aba65daa6a06b33f4ac71ef5ef9308f4057f8e8de10724117fc4d72b55' 
  AND token = 's2Q3NJlrsKbZ5e+LgffSwdWeP7SwZxDWqDIG7XEsA4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}