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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fc6898c6c292daa91f7ab307e4a74f36ed08154059e1b2b4be91d4ccb7f7a7e' 
  AND token = 'eBvnwrMfG+SGbX8StA5SXM0Eyz3hCXkWfjWiw2u0xG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}