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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f65b805cf1a78f80031f0c18a08e8b1fe84849faabc1a687c3ff6bf9447a339a' 
  AND token = 'EeBpc5rpeUXhxvYX5xm9rzQfSxeIrlAeZ0Wwjnum258=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}