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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4addf6f3ed7bf8f9f291f86d17c1de6280e1e9da0adf729379869c5446d9c6' 
  AND token = 'q7w4GYWpXSmuXEK93+ilPsh7coUIFcZ+TwiDD1DTJls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}