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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc4931590457644c3145d4d4e28e822db6be5395d7ecf149f23a2a84bbe3fe4' 
  AND token = 'XdFuvHh7kS14qWzHwbzRdX8mnLgcjfnW7TFoUWb5r38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}