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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19fc580053597ff87b17fb481dcbb68e1fb27e922ee6bb505f43ad74c389b702' 
  AND token = 'trWMMwt+jk0o5t8h5rWrNQki0WfPXJp5lo1ncBGWXCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}