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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40b08cbba528c32f4c078a3ea60601c0515c4164b7a180e959b0090d2027db24' 
  AND token = 'gIL3JI8j/CRZ3JBdK/2JRYeVgmmS9s8qHxKerBP3jrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}