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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75375fc16b0beb4e276e8ff04b09dd3615f4d939b09a2a0301fb9b3c9f173790' 
  AND token = 'a/niVTn/K+LHr6wCMmIIorvQRu7j+Ws+XucloWr8p/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}