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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f61097015f70e3342a681950c7a9af7bfc807acb3643e7b896c6d5e8a115012' 
  AND token = 'npU2e3uJLkhmctf2IKF4AEhR/JjxmVwi9U5nHG4ibUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}