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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6cee0172e8acac367f7cc697861ad10002d39511aa78e758523804b8db03fa2' 
  AND token = 'PU8jdgJglGrDHdj9xdhOENOzR0JSJ90XQ77A+NuzCm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}