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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8c5488d64165b5ea607e8e7aa42d2ece63a43b9e2bd732622f32607893f49c' 
  AND token = 'ga+s4vMVUkd0y1viG/bsppPLiBGz5Q0o4Sw/agQVuEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}