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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118a3c9b0e45e06ffeb095486652bacb7da5163c873e60fd7362e338254c49a4' 
  AND token = 'akc/msT1lWJ2c049p2NKMz/mCPPTMHzdgFrTYaefu30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}