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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8b4ede6d164d69b053306c21ee0c707a49f07ff42c0c56fd3030c4b16fad6ad' 
  AND token = 'MdKamD4QelalIFUZ4ssHaJFy/ylB7uc2N2KBtU+q8Vw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}