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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c24270c1052e2b7db1b2547cfde220c1035b624a0d150a8f9c5b9107390e495' 
  AND token = 'aESBvwWF9Got/v12IC97ZlCfTnv4VWfwaLcTAtQykaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}