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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df45910a4a8c79ac747450ac948bd99ed8fb62e838b4e8c6f4f65d915781788' 
  AND token = '9Dy2Cfh6KgwImTiX4AE1j2fMOnitvpzAOvsxdOYUp5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}