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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dc7351477603e5e5e441b6f899c6414235af9be15df32165181dfa10b0da8a5' 
  AND token = 'e0ZdgDNxGlLRUyUUTi3cq9RtXuBDYWZ9V6njZaa/iDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}