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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065b1ad7329372502328f308514510d66eeb2b06ce72e4babe475bcf781ef09c' 
  AND token = '2kCNpkJp0j6CoRnpoF1UpKMXIxTcFIKBcU9H+MEf0ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}