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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad012e1db71ecb4118e33925341a02a4cfb305c15317bda66ed2654fbfe237f' 
  AND token = 't4RksR6TMOetS0Vsxgtn5uSPPtJXAv/QlCbn8EkqbF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}