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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4293306b2ac6385cb2285e8a0599d62dbdf464cd347a8f0a6a09a60a8208bf63' 
  AND token = 'DOUMMZsuEnTANIBtM7PjrO9pDemHpPZvToXEFQQf0Bs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}