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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d1ee8d620d05a9b095051a7e2f2daff431562f8437ae396c5f39f75a14e2785' 
  AND token = 'Lk9j7b89v9LXE5SUD+LKyCB0BmChMWxOBa3/rS54jdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}