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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ad261965af4730b1eb430c2d2d55a5da44404754b18644a6c7011e27ed06859' 
  AND token = 'sJq+prDSep+BuPftgd/xKNnFIpxuEGz3O5JifW94LIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}