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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73f8f00aeb56431915d2215dc1d44c16a10ac5e6a26cedadf63554fcd0050b96' 
  AND token = 'E+WQa1ZrcEYgh7vyHAuPfhdKzEbrsoOlR5vo5VAio4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}