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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b10f57d7f0539cd28283ee5c6f832eb80ef5e5d346f8a210fedd21de016d134' 
  AND token = '6p8LVGlQFr3JYwRivckDSFhBvYZiaJLsxAu5TrGxmD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}