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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34e30bcce0412fedbe4cb1df95974d16a1a4ae850701f755374a3b3a1912c456' 
  AND token = 'O3A50Z1aEOdZzcc75EH8zmaTDB0cCqCbHxmjBs9VHoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}