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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb234827940859523c596b4d0f05f7336aa58d9cbae342b101412b97a9f67a3' 
  AND token = 'txvL7yRuWLciirekArQ17kkF6YQgKQ3TsL0rvi1Vseg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}