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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c5183b66c02fe189f10272073fd78c75d32f3aeb6e8847a11aa671ac6d72b9c' 
  AND token = 'ofTOqQVjH3hZcW+iDRRIBflsT+bC3peAy8D5+uzvT1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}