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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c1c367ff913fad4933f125fc16a81e072a2801fb08a73c20c177f4eaf10942' 
  AND token = 'D6TDz+3UwbDXPE7ARHPhuV9GohS3QLDZFU5+jB38kk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}