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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78b5ae2c64ddd60fc3086e7080d7521ed0f8c088edc8e64f19c9bdf0b21e9eb4' 
  AND token = '7JCD1EcII0PvpiHOfEv9I15+rcjFAihR0lJVfDj2YmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}