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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80afce9d64948401318ee6b897db2d24ba7b3b524cf69810fcc91766d326aaa1' 
  AND token = 'D5XXKcRHl4jHteShQyoeTJZo0vGbPTUGTIoEu8HqdVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}