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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dea19a751627556d792ef055c75d068ba9fbba5ce17ebdd1d6cab2ffdb23b853' 
  AND token = 'HHFjykw+Kxd0+8GlG4PbfWnQMMfmOktW/lQk6lad1Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}