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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46c98c9fcbb3471c30f276d810090515132404b51aa9898c015ef85dbd2418fb' 
  AND token = 'TeAVGVFRZuAr9rbG/y/gwupM6UKmzftpckbYnSOllQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}