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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05170713d2dbc58e10915ccd42e7c8ae2e80678abe8b69c2643362bcfd5fc631' 
  AND token = 'dMLMQ8ykaErC9kbqEOABMMCMD8zgSOP82XlWtpWN2Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}