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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a57155349fc3d2978004733f0d09060dbae2a45a0be041869d865728799dbd1' 
  AND token = 'n5HWwWh4/4i3/LPkxSTbo5dTuuDzorpSU5zx4DwVcAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}