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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b989e8570a6dc38c2e3675bd43c7e97722cfff1e450481100bf3800211bcd05' 
  AND token = 'JMu608T7ypq26ccof/qZOQJpmOTkDClK6uxu4kpMuQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}