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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a970803454d7c0ba1b842b014659602c4b0ff60a16cb72df1baa6aeea688565' 
  AND token = 'foEez10UMn4TW5Ys6DG0ZfcqOwE4Mo7CF5qTSJ0VAdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}