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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c4f1c92d36e820c646fab6df474213f9c73cdc2ac5bf8427e7adc43cbf1af5' 
  AND token = 'jSHjP7imb5Q7a4MkY/2mVlVP+u7oQfx9jWspDhlAgQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}