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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75f01e0b25c0215439ecbd3ccb80bcc42b109b38ebc2a73efd602f9e116558a9' 
  AND token = 'oWyvn0tabfw/qLLcXc3kYwh+WEfQ7zkSyTsS5xZXNl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}