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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff4bc486ab0af69cdb14a5b179d2686a016e8fb4b5ea1eb11657148db202a8ce' 
  AND token = 'wr7nu+uMO/Vo5hWNXyuNOkM7wPCTsxqFYAKXaN+OstE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}