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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6a87485327155cac459dabb7830a4f5e4dcbbee940e157fffe2f6d2352eb561' 
  AND token = 'fQdH38OtLKaCdycW8jEmtzdXLT9PS2SugVX3yntJRf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}