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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f49c6cf9a9245ef358f00278063f1ce6c029ebced3d95281b7cb8e4f5bbdce9' 
  AND token = '4ctGfYAxCimfClBcUsVZqhfkX2o4+8ZY3/0mydSWgcQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}