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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8150ac2817aebeff59c0736d11e9c53f6415cbc20e94adf47b3fa253cf562160' 
  AND token = 'IIi164ZIdRm7bxiAkhxaQsM4dOc70jShXuyWCrszTVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}