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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57f453bc8a89ff1e6586e83b72b8de33c1921252f01b7fd2d349de5586e7621e' 
  AND token = 'G+cbL0zfSExa0TqOC7h+2vLj1HmdACydfX3BN5+3xHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}