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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e2c6c8a0b2b92be4f4fde8e1f9b9ad8f2935fde6726dd4977dc13b88727b720' 
  AND token = 'yA8fICGoRo3dwV2xxvbQx1YlW+CGTGHuZ+VEClmLtNs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}