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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f27adf38a887107759e78fdc7a6788b8297e2e56a9a9b237276f95cf66951c48' 
  AND token = 'dJItDSu/XoXz6T6dhN+55iR6q5mIHoRb1GLYF70LF50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}