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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a1c247cc5c6998961621abfd4e0cd66c0ecbf516cde1fda04f889978904520a' 
  AND token = 'xhGN4HERyM8ATGGCwc7Ml70wsH8B9Ggh7WrT+g+9CDE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}