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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6182ce53425ea86ffaaa5e7bed0054bdb8364cb625ccd721c2a441942b75ba4d' 
  AND token = 'KIKkH0n+NM2NaK1r3Zvv6AYX9Iy9eoO59DvBKAXibbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}