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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef9ceaf3104fd718f7604e155aa45708ada70a55dde030ca6d2a6ec67b70d105' 
  AND token = '29VPQ05pqLqJ6/MHme/EQoU3rrAcjg+CR8Q8ZeAmsvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}