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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd40753db90357d9cbf9e2fa1e3045dfc612c5651fc81389204016fa4c886033c' 
  AND token = 'nVq7ibdb5gx/SL1o6Do0MQCw5505Qd/GuPnCFA6ubGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}