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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d897538ca962dc5b07bfa2da272766725e5f85a912dada67ca4d41b38726801' 
  AND token = 'WAMJb/k2eRXitLpbJcBWW9/F6cx+zJtLi/Ms8kSgeA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}