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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad6383d981f67245c4a103c2b4c5c0716b108852141126189be60174caaa44d9' 
  AND token = 'OoUpBQ/PFm7BFLysrinsmcCo8lyV+xMA5CcHoCb8+b4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}